Rhinovirus-induced first wheezing episode predicts atopic but not nonatopic asthma at school age
نویسندگان
چکیده
منابع مشابه
Minna Lukkarinen – THE RISK OF SCHOOL-AGE ASTHMA AFTER THE FIRST SEVERE RHINOVIRUS-INDUCED WHEEZING
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متن کاملAirway Epithelium in Atopic and Nonatopic Asthma: Similarities and Differences
Asthma is an inflammatory disorder of the airways, and the airway epithelium has the central role in its pathogenesis. In general, the airway inflammation is characterised by the infiltration of the epithelium and submucosa by a range of inflammatory cells driven largely by Th-2 lymphocytes, eosinophils, and mast cells. The pathogenic mechanisms of nonatopic asthma in comparison to its atopic c...
متن کاملPredictive factor for first wheezing episode.
The aim of study was to evaluate various risk in patients who were hospitalized with moderate to severe virus-induced wheezing. Infants hospitalized with virus-induced wheezing were enrolled in the study. Respiratory viruses were detected in nasopharyngeal swab and total IgE levels and skin prick tests were performed in all patients. The mean age of the patients was 11.2±9 months. The most comm...
متن کاملRhinovirus wheezing illness and genetic risk of childhood-onset asthma.
BACKGROUND Both genetic variation at the 17q21 locus and virus-induced respiratory wheezing illnesses are associated with the development of asthma. Our aim was to determine the effects of these two factors on the risk of asthma in the Childhood Origins of Asthma (COAST) and the Copenhagen Prospective Study on Asthma in Childhood (COPSAC) birth cohorts. METHODS We tested genotypes at the 17q2...
متن کاملP57 - Prognostic factors for asthma at school age in infants with atopic dermatitis
Materials and methods 89 infants with AD aged 3 to 24 months were recruited and followed up until the age of 8 years. The severity of AD at the time of the initial visit was calculated by using the SCORAD index, whereas the laboratory parameters determined were: peripheral blood eosinophil count, serum ECP, total IgE and specific IgE levels for a panel of food and inhaled allergens. Every secon...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2017
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2016.12.991